Welcome to DepLink

A project to systematically link genetic and pharmacologic dependencies of cancer

Explore


Broad DepMap

Genes

Cell lines

Sanger DepMap

Genes

Cell lines

PRISM

Drugs

Cell lines

GDSC

Drugs

Cell lines

LINCS

Drugs

Genes

Functions

DepLink offers a variety of options to observe genetic and pharmaceutical perturbations on cancer

Click the links below to get started

Global Network

Networks

Explore key connections through DepLink's target networks


Gene

1. Query Gene 

Find and analyze gene knockouts and drug treatments with similar perturbation effects as the selected gene


2. Query Gene List 

Observe distributions of dependencies among multiple genes at a time and search for drug coperturbances

Drug

3. Query Drug 

Find and analyze gene knockouts and drug treatments with similar perturbation effects as the selected drug


4. Query New Drug

Locate known drugs sharing similar biochemical features with a new compound using SMILE code


Help

Learn about the full range of DepLink's functions and how to utilize them